Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.600 None 0.971 797 21 1979 2020
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.600 None 0.969 675 3 1975 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.600 None 0.921 546 15 1986 2020
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1
P30556 angiotensin II receptor type 1 G-protein coupled receptor 440 0.423 0.846 5.3E-04 0.600 None 0.944 198 7 1993 2020
Entrez Id: 6462
Gene Symbol: SHBG
SHBG
P04278 sex hormone binding globulin 368 0.438 0.808 1.3E-06 0.100 None 0.942 121 3 1999 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.600 None 0.983 116 1 1993 2020
Entrez Id: 54535
Gene Symbol: CCHCR1
CCHCR1
Q8TD31 coiled-coil alpha-helical rod protein 1 193 0.505 0.808 1.0E-16 0.100 None 0.939 114 3 1999 2020
Entrez Id: 8991
Gene Symbol: SELENBP1
SELENBP1
Q13228 selenium binding protein 1 Immune response 214 0.493 0.846 3.2E-16 0.100 None 0.939 114 4 1999 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.600 None 0.944 107 0 2003 2020
Entrez Id: 5443
Gene Symbol: POMC
POMC
P01189 proopiomelanocortin 873 0.356 0.846 1.2E-04 0.400 None 0.989 91 0 1974 2020
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.100 None 0.989 88 0 1999 2020
Entrez Id: 738
Gene Symbol: VPS51
VPS51
Q9UID3 VPS51 subunit of GARP complex 292 0.452 0.846 1.1E-08 0.100 None 0.988 86 0 1999 2020
Entrez Id: 4306
Gene Symbol: NR3C2
NR3C2
P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 287 0.469 0.846 0.84 0.200 None 1.000 81 7 1995 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 1.000 77 5 1997 2020
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.400 None 0.947 75 1 1989 2020
Entrez Id: 1628
Gene Symbol: DBP
DBP
Q10586 D-box binding PAR bZIP transcription factor Nucleic acid binding 105 0.556 0.731 0.23 0.100 None 0.944 72 0 1988 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.600 None 0.972 71 2 1998 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 0.970 66 3 1999 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.600 None 1.000 66 0 1998 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.700 None 1.000 62 10 1999 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.881 59 7 1993 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.400 None 0.943 53 4 2002 2020
Entrez Id: 65266
Gene Symbol: WNK4
WNK4
Q96J92 WNK lysine deficient protein kinase 4 Kinase 43 0.644 0.538 6.9E-25 0.500 None 0.909 44 2 2003 2020
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2
Q13873 bone morphogenetic protein receptor type 2 Kinase 146 0.538 0.654 1.00 0.200 None 1.000 40 1 2002 2020
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.100 None 0.974 39 0 2003 2020